Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity linked to bortezomib, a proteasome inhibitor Utilized in the treatment method of several myeloma. Its synthesis or examine is critical for making certain the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound during the synthesis of imatinib, a drug that targets precise forms of cancer, including Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers which include breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their review is essential for optimizing the output approach and making sure Bortezomib intermediate substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is made use of to treat breast cancer, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Employed in the therapy of breast cancer. Many intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers including ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the cure of colorectal most cancers and compact cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-nine): This TBTU compound is involved with the synthesis of adamantane derivatives, that have many applications, such as antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for style 2 diabetes that inhibits the enzyme DPP-four to control blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of assorted gluconic acid derivatives, which are Employed in food stuff, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication employed to handle sort 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).